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Human Plasma Proteins
Showing
1 to 57 of 57 Human Plasma Proteins
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| 2HK 1301 Two Chain High Molecular Weight Kininogen |
£
price not available in open catalogue/1.0 mg |
ERL offers the two chain Kinin-free form of Kininogen. This is prepared by Kallikrein digestion of Kininogen which is then repurified to remove traces of Kallikrein.
Buffer composition = 4 mM Sodium Acetate-HCl/0.15 M NaCl/pH 5.3
*Extinction Coefficient (1%) = 7.01
Molecular Weight = 110,000 daltons
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| APC Human Activated Protein C |
£
price not available in open catalogue/0.1 mg |
Activated Protein C (APC) is a serine protease derived from the two chain vitamin K dependent zymogen, Protein C. APC inhibits blood coagulation through the selective inactivation of the cofactors Va and VIIIa. APC is prepared from protein C by activation with purified thrombin. This thrombin is removed after activation by ion exchange chromatography. Activated Protein C purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.
Buffer composition = 20 mM Tris-HCl/0.1 M NaCl/ pH 7.4
*Extinction Coefficient (1%) = 14.5
Molecular Weight = 56,000 daltons
Also available: des-Gla-Human Activated Protein C
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| HAPO-H - Apolipoprotein-H Apolipoprotein-H (B2GP-1) |
£
price not available in open catalogue/0.1 mg |
B2Glycoprotein-1 (B2GP-1), also known as Apolipoprotein-H is a plasma glycoprotein that circulates at a concentration of 200 ug/ml (4 uM). B2GP-1 has been identified as a constituent of chylomicrons, very low density lipoproteins and high density lipoproteins in human plasma. It has also been demonstrated to bind phospholipids, heparin and platelets where it can modulate the activity of adenylate (19%).
Although the precise function(s) are as yet unknown, B2GP-1 has been shown to interfere with blood coagulation by competitively binding to phospholipids exposed during cell activation or damage. Recent evidence also implicates B2GP-1 as a cofactor recognized by some anti-phospholipid antibodies present in autoimmune disorders such as systemic lupus erythematosus (SLE).
Buffer Composition = 20 mM Tris-HCl, 0.3 M NaCl, pH 7.3
Extinction Coefficient = (1%) = 9.4
Molecular Weight = 48,000 daltons |
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| HPZ Human Protein Z |
£
price not available in open catalogue/0.5 mg |
The human protein Z is purified from plasma via a combination of precipitations and column chromatography. HPZ purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol.
Buffer composition = 50mM Tris-HCl/0.1 M NaCl/pH 7.5
*Extinction Coefficient (1%) = 12.0
Molecular Weight = 62,000 daltons
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| FIB 1 Human Fibrinogen, Plasminogen Depleted |
£
price not available in open catalogue/1.0 gm |
Purified from fresh frozen plasma. This protein is homogeneous on 4-20 % SDS-PAGE gels and is greater than 95 % clottable. No other coagulation factors are detected by functional assay. Conversion of soluble Fibrinogen to the insoluble clot-forming fibrin is the terminal stage of blood coagulation.
Buffer Composition = 10 mM Phosphate, 20 mM Citric Acid-HCl, pH 7.4
Extinction Coefficient (1 %) = 15.1
Molecular Weight = 330,000 daltons |
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| FIB 2 Human Fibrinogen, Plasminogen and von Willebrand Factor Free Depleted |
£
price not available in open catalogue/1.0 gm |
Purified from fresh frozen plasma, this protein has been purified using a combination of salt precipitations, affinity and immunoaffinity resins to remove Plasminogen and von Willebrand Factor. In a functional assay this protein is greater than 95 % clottable and is homogeneous on 4-20 % SDS-PAGE gels.
Buffer Composition = 20 mM Sodium Citrate-HCl, pH 7.4
Extinction Coefficient (1 %) = 15.1
Molecular Weight = 330,000 daltons
Also available Peak'1', Peak'2' Fibrinogen and Factor XIII depleted Peak '2' Fibrinogen. |
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| FIB 3 Human Fibrinogen, Plasminogen, von Willebrand Factor and Fibronectin Depleted |
£
price not available in open catalogue/1.0 gm |
Purified from fresh frozen plasma, this protein has been purified using a combination of salt precipitations, affinity and immunoaffinity resins to remove Plasminogen, von Willebrand Factor and Fibronectin. In a functional assay this protein is greater than 95 % clottable and is homogeneous on 4-20 % SDS-PAGE gels.
Buffer Composition = 20 mM Sodium Citrate-HCl, pH 7.4
Extinction Coefficient (1%) = 15.1
Molecular Weight = 330,000 daltons
Also available Peak'1', Peak '2' Fibrinogen and Factor XIII depleted Peak'2' Fibrinogen. |
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| GP2b3a Human GPIIbIIIa |
£
price not available in open catalogue/1.0 mg |
Platelet membrane glycoproteins are involved in platelet adhesion and aggregation. Glycoproteins IIb and IIIa (GPIIb and GPIIIa) constitute the fibrinogen receptor and are required for platelet aggregation. Enzyme Research Laboratories offers GPIIbIIIa purified from human platelets. Glycoprotein IIb consists of 2 disulfide-linked subunits GPIIb, (MW = 125,000) and GPII (MW 23,000) while GPIIIa has only one polypeptide chain (MW 108,000), reduced). GPIIbIIIa migrates on gels as follows: GPIIb 136,000 non-reduced and 125,000 reduced. GPIIIa is 97,000 non-reduced and 108,000 reduced. Protein concentration is determined by the Bradford method.
Buffer Composition = 20 mM Tris-HCl, 0.1 M NaCl, 0.1% Triton X-100, 1 mM CaCl2, 0.05% NaN3, 50 Glycerol, pH 7.4.
Extinction Coefficient (1%) = 9.1 |
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| HAT Human Antithrombin |
£
price not available in open catalogue/1.0 mg |
Purified from fresh frozen human plasma. AT is a single chain glycoprotein which is considered to be the main physiological inhibitor of Thrombin and Factor Xa. In the presence of heparin, the inhibition of Thrombin and Factor Xa is enhanced from 300 to 1,000 fold. AT purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol.
Buffer Composition = 20 mM Tris-HCl, 0.1 M Citric Acid, 0.15 M NaCl, pH 8.3
Extinction Coefficient (1 %) = 6.5
Molecular Weight = 58,000 daltons |
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| HCII Human Heparin Cofactor II (HCII) |
£
price not available in open catalogue/0.5 mg |
Prepared from fresh frozen human plasma. Heparin Cofactor II is a single chain glycoprotein with a MW of 65,600 daltons. HCII is a specific inhibitor of Thrombin with increased activity in the presence of heparin. HCII purity is determined by SDS-PAGE and the activity is measured by the ability to inhibit Thrombin in the presence of saturating concentrations of heparin.
Buffer Composition = 20 mM Tris-HCl, 0.15 M NaCl, pH 7.3 containing 0.02% NaN3(w/v).
Extinction Coefficient (1 %) = 9.1
Molecular Weight = 65,600 daltons |
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| HFIX 1009 Human Factor IX (Christmas Factor) |
£
price not available in open catalogue/100 U (0.5 mg) |
Prepared from fresh frozen human plasma. The protein purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol. Activity is determined via clotting assay. Human Factor IX, activated by either the Contact or Tissue Factor Pathway, is responsible for the activation of Factor X to Xa.
Buffer Composition = 20 mM Tris-HCl, 0.1 M NaCl, 1 mM Benzamidine, pH 7.4
Extinction Coefficient (1%) = 13.2
One Unit = 5 ug
Molecular Weight = 56,000 daltons |
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| HFIXa 1070 Human Factor IXa,a
*This product is no longer available* |
£
price not available in open catalogue/100 U (0.5 mg) |
Prepared from Human Factor IX by activation with Russell's Viper Venom (RVV-X). This RVV-X cleaves a single internal Arg-Val peptide bond in Factor IX. The RVV-X is removed after activation. Complete activation is observed on SDS-PAGE. The protein purity is determined by SDS-PAGE and shows total reduction upon incubation with 2-mercaptoethanol. This form of Factor IX has about 50 % of the coagulant activity of Human Factor IXa,b.
Buffer Composition = 20 mM Tris-HCl, 0.1 M NaCl, pH 7.4
Extinction Coefficient (1%) = 14.9
One Unit = 5 ug
Molecular Weight = 56,000 daltons |
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| HFIXa 1080 Human Factor IXa,b |
£
price not available in open catalogue/100 U (0.5 mg) |
Prepared from Human Factor IX by activation with Bovine Factor XIa. This Bovine Factor XIa is removed after activation. Complete activation is observed by SDS-PAGE. The Factor XIa activates Factor IX in a two step reaction. In the first step an internal Arg-Ala bond is cleaved and in the second step an Arg-Val bond is cleaved. The second cleavage leads to the liberation of an activation peptide from the NH2-terminal portion of the heavy chain to produce Factor IXa,b.
Buffer Composition = 20 mM Tris-HCl, 0.1 M NaCl, pH 7.4
Extinction Coefficient (1%) = 14.3
One Unit = 5 ug
Molecular Weight = 45,000 daltons |
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| FN Human Fibronectin |
£
price not available in open catalogue/1.0 mg |
At 300 ug/ml, plasma fibronectin is second to fibrinogen in abundance. It is a glycoprotein, composed of two subunits of approximately 220 kD each and participates in several cell-substratum adhesive interactions. Fibronectin binds to collagen, fibrinogen, fibrin, heparin. Enzyme Research Laboratories offers fibronectin purified by gelatin affinity chromatography followed by heparin chromatography.
Buffer Composition = 10 mM HEPES, 0.15 M NaCl, pH 7.5
Extinction Coefficient (1%) = 12.8
Molecular Weight = 440,000 daltons |
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| HFVII 1007 Human Factor VII (Proconvertin) |
£
price not available in open catalogue/0.1 mg |
Prepared from fresh frozen human plasma. Human Factor VII is a single chain vitamin K-dependent glycoprotein found in trace quantities in plasma (0.5 mg/Liter) In the Tissue Factor Pathway of coagulation, Human Factor VIIa, in the presence of calcium ions and tissue factor, activates Factor IX and X to their enzymatically active forms, Factor IXa and Xa. Purity is determined by SDS-PAGE.
Buffer Composition = 20 mM Tris-HCl, 0.1 M NaCl, 1 mM Benzamidine, pH 7.4
Extinction Coefficient (1%) = 13.9
Molecular Weight = 50,000 daltons |
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| HFVIIa Human Factor VIIa |
£
price not available in open catalogue/0.1 mg |
Prepared from purified Human Factor VII using Human Factor XIIa. The Factor XIIa is removed using affinityg chromagtography. Purity is determined by SDS-PAGE. Human Factor VIIa reduces to 29,500 and 23,500 with the addition of 2-mercaptoethanol. Activity is determined via clotting assay. Factor VIIa, in the presence of calcium ions and the Tissue Factor, activates Factors IX and X to their enzymatically active forms, Factor IXa and Xa.
Buffer Composition = 20 mM Tris-HCl, 0.1 M NaCl, pH 7.4
Extinction Coefficient (1%) = 13.9
Molecular Weight = 50,000 daltons
*(Also available des-Gla Human Factor VIIa and Factor VIIa inactivated - Please enquire) |
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| HFX 1010 Human Factor X (Stuart Prower Factor) |
£
price not available in open catalogue/100 U (0.8 mg) |
Prepared from fresh frozen human plasma. The purity of this Vitamin K-dependent protein is determined by SDS-PAGE gels and shows total reduction upon incubation with 2-mercaptoethanol. Activity is determined via clotting assay. Human Factor X, once activated via the Contact Factor Pathway or Tissue Factor Pathway, is responsible for the conversion of Prothrombin to Thrombin.
Buffer Composition = 20 mM Tris-HCl, 0.1 M NaCl, 1 mM Benzamidine, pH 7.4
Extinction Coefficient (1%) = 11.6
One Unit = 8 ug
Molecular Weight = 58,800 daltons
*(Also available Des-Gla Human Factor X - Please enquire) |
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| HFXa 1011 Human Factor Xa |
£
price not available in open catalogue/100 U (0.8 mg) |
Human Factor Xa is prepared from homogeneous Human Factor X by activation with Russell's Viper Venom (RVV-X). This RVV-X is removed after activation. Complete activation is observed on 10 % SDS-PAGE gels. Factor Xa as part of the prothrombinase complex along with Factor Va, phospholipids and calcium ions
catalyze the rapid conversion of Prothrombin to Thrombin.
Buffer Composition = 20 mM Bis-Tris, 0.7 M NaCl, pH 6.0
Extinction Coefficient (1 %) = 11.6
One Unit = 8 ug
Molecular Weight = 46,000 daltons |
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| HFXI 1111 Human Factor XI (Plasma Thromboplastin Antecedent) |
£
price not available in open catalogue/0.1 mg |
Prepared from fresh frozen human plasma. Human Factor XI is a glycoprotein of molecular weight 160,000. This protein migrates as a single band on 6 % SDS-PAGE gels in the absence of reducing agents. Human Factor XI is comprised of two identical polypeptide chains linked by disulphide bonds which yield a single band at 80,000 upon reduction with 2-mercaptoethanol. The specific clotting activity of purified Human Factor XI is 180-200 units/mg. In vivo, Factor XI is activated to Factor XIa by Factor XIIa. The resulting Human Factor XIa consists of two heavy and two light chains held together by disulphide bridges.
Buffer Composition = 4 mM Sodium Acetate-HCl, 0.15 M NaCl, pH 5.3
Extinction Coefficient (1 %) = 13.1
Molecular Weight = 160,000 daltons |
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| HFXIII 1313 Human Factor XIII (Fibrin Stabilizing Factor) |
£
price not available in open catalogue/0.25 mg |
Human Factor XIII is a tetramer composed of two pairs of chains held together by non-covalent bonds. After activation of the zymogen via Thrombin to its active enzyme form, Factor XIIIa is responsible for catalyzing the formation of covalent bridges between fibrin units to increase the elasticity of the clot network. The resulting cross-linked fibrin is very insoluble and resistant to lysis. Enzyme Research Laboratories offers the
zymogen form of Human Factor XIII (a2b2).
Buffer Composition = 50 mM Tris-HCl, 0.1 M NaCl, 1 mM EDTA, 10 u/ml Trasylol, 20% Glycerol, pH 7.5
Extinction Coefficient (1 %) = 13.8
Molecular Weight = 320,000 daltons |
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| HGT Human Gamma Thrombin |
£
price not available in open catalogue/1.0 mg |
A non-clotting derivative of Thrombin produced from human alpha Thrombin by controlled digest with Trypsin-Sepharose. Gamma Thrombin is a non-coagulant form of Thrombin that retains much of its platelet activating capacity. Gamma Thrombin purity is determined by SDS-PAGE.
Buffer Composition = 10 mM Sodium Acetate, 0.75 M NaCl, pH 6.0
Molecular Weight = 12,000 daltons
Concentration determined by BCA. |
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| HK 1300 Single Chain High Molecular Weight Kininogen (Fitzgerald Factor) |
£
price not available in open catalogue/1.0 mg |
High Molecular Weight Kininogen (HK) is a non-enzymatic cofactor of the contact activation system. HK is thought to have two functions in the contact activation system. First, HK links Prekallikrein to a negatively charged surface thereby allowing activation of Kallikrein by surface bound Factor a-XIIa. HK also forms a complex with Factor XI and accelerates its activation to XIa by a-XIIa. Additionally HK serves as a source of Bradykinin, a potent vasoactive peptide important in hypotension studies. The protein purity is determined by SDS-PAGE.
Buffer Composition = 4 mM Sodium Acetate-HCl, 0.15 M NaCl, pH 5.3
Extinction Coefficient (1 %) = 7.01
Molecular weight = 120,000 daltons |
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| HP 1002 Human Prothrombin (Factor II) |
£
price not available in open catalogue/100 U (9 mg) |
Prepared from fresh frozen human plasma. Human Prothrombin is a glycoprotein of molecular weight 72,000 and consists of a single polypeptide chain. Activation of Prothrombin by Factor Va,Xa and phospholipids yields the serine protease Thrombin. Prothrombin purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol.
Buffer Composition = 20 mM Tris-HCl, 0.1 M NaCl, pH 7.4
Extinction Coefficient (1 %) = 13.6
One Unit = 90 ug
Molecular Weight = 72,000 daltons
*(Also available des-Gla Human Prothrombin & Prothrombin Fragment 1 and 2- Please enquire). |
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| HPC 1001 Human Protein C |
£
price not available in open catalogue/0.1 mg |
GHPC is purified from fresh frozen human plasma using a combination of salt precipitations and column chromatography. This protein is determined by SDS-PAGE and shows total reduction upon incubation with 2-mercaptoethanol. Protein C is activated to the serine protease, Activated Protein C (APC)by Thrombin or the complex of Thrombin/Thrombomodulin and is a potent anticoagulant through the selective inactivation of Factors Va and VIIIa.
Buffer Composition = 20 mM Tris-HCl, 0.1 M NaCl, 1 mM Benzamidine, pH 7.4
Extinction Coefficient (1%) = 14.5
Molecular Weight = 62,000 daltons
*(Also available des-Gla Human Protein C - Please enquire) |
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| HPg 2001 Human Glu-Plasminogen |
£
price not available in open catalogue/1.0 mg |
Purified from fresh frozen human plasma. The protein purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol. No plasmin activity is detected using the chromogenic substrate S-2251. Plasminogen is activated to the serine protease Plasmin via urokinase, streptokinase or tissue plasminogen activator.
Buffer Composition = 50 mM Tris-HCl, 0.1 M NaCl, pH 7.4
Extinction Coefficient (1 %) = 17.0
Molecular Weight = 90,000 daltons
Forms 1 and 2 also available. |
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| HPK 1302 Human Prekallikrein (Fletcher Factor) |
£
price not available in open catalogue/1.0 mg |
Purified from fresh frozen human plasma. Human Prekallikrein is a single chain gamma globulin glycoprotein that participates in the early phase of contract activation, kinin formation and fibrinolysis. Prekallikrein purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol. Activity is determined via clotting assay.
Buffer composition = 4 mM Sodium Acetate-HCl, 0.15 M NaCl, pH 5.3
Extinction Coefficient (1%) = 11.7
Molecular Weight = 86,000 daltons |
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| HPKa 1303 Human Kallikrein |
£
price not available in open catalogue/1.0 mg |
Activation of Prekallikrein with Factor a-XIIa produces the enzymatically active Kallikrein. Kallikrein is a serine protease which consists of a heavy chain (molecular weight 52,000) and light chains (molecular weights either 36,000 or 33,000) linked by disulphide bridges. Kallikrein possesses enzymatic activity towards Factor XII, High Molecular Weight Kininogen, Plasminogen, Factor XI, Factor IX, Factor VII, prorenin and the complement system. After activation, the activating enzyme Factor XIIa is removed by affinity chromatography. Human Kallikrein purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.
Buffer Composition = 4 mM Sodium Acetate-HCl, 0.15 M NaCl, pH 5.3
Extinction Coefficient (1 %) = 11.7
Molecular Weight = ~86,000 daltons |
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| HPlasmin Human Plasmin |
£
price not available in open catalogue/1.0 mg |
Prepared from Glu-Plasminogen using urokinase which is not removed after activation. Purity is judged by SDS-PAGE. Plasmin is a two chain serine protease linked by 2 disulfide bonds. Among other roles, Plasmin is responsible for the lysis of the fibrin clot, thus producing fibrin degradation products. (FDP's)
Buffer Composition = 0.1 M HEPES-HCl, 0.1 M Sodium Acetate, pH 8.5
Extinction Coefficient (1 %) = 17.0
Molecular Weight = 83,000 daltons |
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| HPS Human Protein S |
£
price not available in open catalogue/1.0 mg |
Protein S exists in two forms in human plasma, as the free protein and in complex with C4b-binding protein. Enzyme Research Laboratories offers the free protein from plasma which serves as a cofactor for the anticoagulant activity of Activated Protein C. Human Protein S is a single chain glycoprotein with a molecular weight of 69,000. HPS purity is determined by SDS-PAGE.
Buffer Composition = 20 mM Tris-HCl, 0.1 M NaCl, 1 mM Benzamidine, pH 7.4
Extinction Coefficient (1%) = 9.5
One Unit = 10 ug
Molecular Weight = 69,000 daltons |
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| HT 1002a Human a-Thrombin (Factor IIa) |
£
price not available in open catalogue/1000 NIH U |
Prepared from human Prothrombin by activation with Factor Xa, Factor Va and phospholipid. Human Thrombin purity is determined by SDS-PAGE. This activated enzyme has a minimum activity of 2,700 NIH units/mg when compared to NIH standard Thrombin.
Buffer Composition = 50 mM Sodium Citrate, 0.2 M NaCl, 0.1% PEG-8000, pH 6.5
Extinction Coefficient (1%) = 18.3
Molecular Weight = 37,000 daltons |
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| HFXIa 1111a Human Factor XIa |
£
price not available in open catalogue/0.1 mg |
Prepared from Human Factor XI using Human Factor XIIa. This XIIa is removed using a corn trypsin inhibitor column. Complete activation is observed by SDS-PAGE. Factor XI, through the contact factor pathway cascade, is activated to Factor XIa via Factor XIIa and High Molecular Weight Kininogen. During activation by Factor XIIa and HK, FXI undergoes proteolytic cleavage in which the Mr=80,000 chain reportedtly is cleaved to a heavy and light chain with Mr of about 48,000 and 33,000. This Factor XIa is responsible for the activation of Factor IX to Factor IXa. Unlike other examples of activation of vitamin K-dependant blood-clotting proteins, Factor XIa proteolysis of Factor IX does not require membrane surfaces.
Buffer composition = 4 mM Sodium Acetate-HCl, 0.15 M NaCl, pH 5.3
*Extinction Coefficient (1%) = 13.1
Molecular Weight = 160,000 daltons. |
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| HXII 1212 Human Factor XII (Hageman Factor) |
£
price not available in open catalogue/0.5 mg |
Purified from fresh frozen human plasma. Human Factor XII is part of the contact activation system. Human Factor XII is a single chain glycoprotein with a molecular weight of approximately 80,000. Once activated, principally from the action of Kallikrein, Factor XII is converted into the active serine protease (Factor a-XIIa) that functions in the in vivo initiation of blood coagulation, fibrinolysis and kinin formation. Human Factor XII has been purified by ion exchange chromatography. Protein purity is determined by SDS-PAGE and activity is determined via clotting assay.
Buffer Composition = 4 mM Sodium Acetate-HCl, 0.15 M NaCl, pH 5.3
Extinction Coefficient (1 %) = 14.1
Molecular Weight = 80,000 daltons |
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| HXIIa 1212a Human Factor a-XIIa (Activated Hageman Factor) |
£
price not available in open catalogue/0.5 mg |
Human Factor a-XIIa is a serine protease responsible for the activation of Factor XI to XIa in the contact activation system. Human Factor XII and Prekallikrein are thought to be involved in a reciprocal activation mechanism in which XIIa activates Prekallikrein to Kallikrein which in turn converts Factor XII to XIIa. Factor XIIa activates Factor XI to XIa thereby triggering the Contact Factor cascade. Enzyme Research Laboratories offers Factor a-XIIa which is activated by the autoactivation process with Dextran Sulphate and re-purified to remove the activator. The protein purity is determined by SDS-PAGE and activity is determined via clotting assay.
Buffer Composition = 4 mM Sodium Acetate-HCl, 0.15 M NaCl, pH 5.3
Extinction Coefficient (1 %) = 14.1
Molecular Weight = 80,000 daltons |
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| LPg 2002 Human Lys-Plasminogen |
£
price not available in open catalogue/1.0 mg |
Purified from homogeneous Glu-Plasminogen by activation with Plasmin. This activation results in the release of a 76 amino acid peptide (Glu-Lys76). This Lys 77- Plasminogen can be readily converted to Lys 77-Plasmin by any of the common plasminogen activators. The protein purity is determined by SDS-PAGE.
Buffer Composition = 50 mM Tris-HCl, 0.1 M NaCl, pH 7.4
Extinction Coefficient (1 %) = 17.0
Molecular Weight = 83,000 daltons |
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| APCGD Human Activated Protein C Des-Gla |
£
price not available in open catalogue/0.1 mg |
| Human Activated Protein C Des-Gla |
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| PF4 Platelet Factor 4 (PF4) |
£
price not available in open catalogue/0.1 mg |
Platelet Factor 4 is purified from Human platelets by affinity chromatography and gel filtration. It has a molecular weight of 29,000 daltons and is made up of 4 identical subunits of 7,800 daltons each.
Buffer Composition = 50 mM Tris-HCl, 1.5 M NaCl, 0.02% NaN3, pH 7.3
Extinction Coefficient = (1%) = 2.6
Molecular Weight = 29,000 daltons |
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| TAFI Human Thrombin Activatable Fibrinolysis Inhibitor (Procarboxypetidase B) |
£
price not available in open catalogue/0.1 mg |
Thrombin Activatable Fibrinolysis Inhibitor (TAFI), also known as plasma procarboxypeptidase-B and carboxypeptidase-U, is a single chain glycoprotein with a mass of 58,000 daltons. TAFI is purified from normal human plasma using immunoaffinity and ion-exchange chromatography.
Buffer Composition = 20mM HEPES, 0.2 M NaCl, pH 7.4
Extinction Coefficient (1%) = 20.2
Molecular Weight = 58,000 daltons |
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| HTI Human alpha Thrombin Inactivated |
£
price not available in open catalogue/1.0 mg |
| Human alpha Thrombin active site blocked |
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| HPGD Prothrombin Des-Gla |
£
price not available in open catalogue/10.0 mg |
| Enzyme Research Laboratories now offers this protein with the y-carboxyglutamic acid region removed |
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| F1 Prothrombin Frag. 1 |
£
price not available in open catalogue/1.0 mg |
| Please inquire |
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| F2 Prothrombin Frag. 2 |
£
price not available in open catalogue/1.0 mg |
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| HFVIIaGD Human Factor VIIa Des-Gla |
£
price not available in open catalogue/0.1 mg |
| Enzyme Research Laboratories now offers this protein with the γ-carboxyglutamic acid region removed. |
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| HFVIIai Human Vlla Inactivated |
£
price not available in open catalogue/0.1 mg |
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| HPCGD Human Protein C Des-Gla |
£
price not available in open catalogue/0.1 mg |
| Enzyme Research Laboratories now offers this protein with the γ-carboxyglutamic acid region removed. |
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| HFIXai Human Factor IX a,b Inactivated |
£
price not available in open catalogue/100 units (0.5 mg) |
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| HFXGD Human Factor X Des-Gla |
£
price not available in open catalogue/1.0 mg |
| Enzyme Research Laboratories now offers this protein with the γ-carboxyglutamic acid region removed. |
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| HFXai Human Factor Xa Inactivated |
£
price not available in open catalogue/100 units (0.5 mg) |
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| HFXab Human Factor Xa beta |
£
price not available in open catalogue/100 units (0.8 mg) |
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| HFXabGD Human Factor Xa beta Des-Gla |
£
price not available in open catalogue/1.0 mg |
| Enzyme Research Laboratories now offers this protein with the γ-carboxyglutamic acid region removed. |
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| HFXIIab Human Factor XIIa beta |
£
price not available in open catalogue/0.1 mg |
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| HFXIIIa 1314 Human Factor XIIIa |
£
price not available in open catalogue/0.25 mg |
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| APCi Human Activated Protein C Inactivated |
£
price not available in open catalogue/0.1 mg |
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| PKA Human Prekallikrein Activator |
£
price not available in open catalogue/2.0 mL |
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| P1FIB Peak'1' Purified Fibrinogen |
£
price not available in open catalogue/10.0 mg |
| Contains mostly intact Aα subunit chains, is free of plasminogen, factor XIII, fibronectin, and other non-fibrinogen protein contaminants. Peak'1'fibrinogen molecules each contain two copies of the platelet-binding γA chain C-terminal sequence and are ideal substrates for factor XIII assay. |
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| P2FIB Peak'2' Purified Fibrinogen |
£
price not available in open catalogue/10.0 mg |
| Contains measurable amonts of factor XIII activity because the factor XIII B subunits bind to the γ chains and bring catalytic A subunits along with them. Thus Peak'2' fibrinogen serves as a 'carrier'for factor XIII in blood. The γ chain lacks the platelet recognition sequence but, becomes crosslinked to dimers by factor XIIa. |
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| HPKi Human Inactivated Prekallikrein |
£
price not available in open catalogue/1.0 mg |
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| a2-AP a2-Antiplasmin (a2-AP) |
£
price not available in open catalogue/0.1 mg |
α2-Antiplasmin (α2AP), also known as α2Plasmin Inhibitor, is a plasma glycoprotein that is a member of the SERPIN family of proteinase inhibitors. α2AP is the primary fast-acting inhibitor of plasmin in vivo, but has also been reported to inhibit other enzymes such as trypsin, elastase, and Activated Protein C. α2AP is purified from normal human plasma using immunoaffinity and ion-exchange chromatography. Purified α2AP activity is determined by titration with purified plasmin.
Buffer Composition = 20 mM Tris-HCl/0.15 M NaCl/pH 7.3
Extinction Coefficient (1%) = 7.0
Molecular Weight = 70,000 daltons
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