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Human Activated Protein C

Catalogue Number: APC
Size: 0.1 mg

Activated Protein C (APC) is a serine protease derived from the two chain vitamin K dependent zymogen, Protein C. APC inhibits blood coagulation through the selective inactivation of the cofactors Va and VIIIa. APC is prepared from protein C by activation with purified thrombin. This thrombin is removed after activation by ion exchange chromatography. Activated Protein C purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.

Buffer composition = 20 mM Tris-HCl / 0.1 M NaCl / pH 7.4

Extinction Coefficient (1%) = 14.5

Molecular Weight = 56,000 daltons

 

Supplied LYOPHILIZED. Shipped at ambient temperature.

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