Bovine Protein C

Catalogue Number: BPC 1003
Size: 1.0 mg

Purified from fresh citrated bovine plasma using a combination of salt precipitations and column chromatography. Protein purity is determined by SDS-PAGE and shows total reduction upon incubation with 2-mercaptoethanol. Protein C is activated to gthe serine protease, Activated Protein C (APC), by a-thrombin or the complex of a-thrombin/Thrombomodulin. This Activated Protein C is a potent anticoagulant through the selective inactivation of Factor Va and Factor VIIIa.

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Bovine Prothrombin (Factor II)

Catalogue Number: BP 1004
Size: 10 mg

Prepared from freshly collected bovine plasma. Bovine Prothrombin is a glycoprotein of molecular weight 70,000 and consists of a single polypeptide chain. Activation of Prothrombin by the Prothrombnase complex (FXa, FVa, PL and Ca++)yields the serine protease Thrombin. Prothrombin purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol.

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Bovine Factor IX

Catalogue Number: BFIX 1005
Size: 0.5 mg

Prepared from freshly collected bovine plasma. Protein puriry is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol. Activated Factor IX (activated via Factor XIa or the Factor VIIa/tissue factor/phospholipid complex is responsible for the activation of Factor X to Xa.

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Bovine Factor X

Catalogue Number: BFX 1006
Size: 1.0 mg

Prepared from freshly collected bovine plasma. Bovine Factor X, when activated via the contact factor pathway or tissue factor pathway, is responsible for the conversion of Prothrombin to Thrombin. The protein purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.

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Bovine Plasminogen

Catalogue Number: BPg
Size: 1.0 mg

Purified from freshly collected bovine plasma. The protein purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol. No Plasmin activity is detected using chromogenic substrate S-2251. Plasminogen is activated to the serine protease plasmin via urokinase, streptokinase or tissue plasminogen activator.

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