- Human Coagulation
- Bovine Coagulation
- Venom Proteins
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- r2 Diagnostics
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Snake Venom Enzymes
BatroxobinCatalogue Number: 101-04
Size: 100 BU
Batroxobin is a thrombin-like proteolytic enzyme isolated from the venom of Bothrops atrox Maranhoa. It splits the 16 Arg-17 Gly bond in the Aα-chain of fibrinogen and causes the release of fibrinopeptide A and the formation of fibrin I monomer or Des-AA-monomer which spontaneously aggregates into a clot of fibrin I. Batroxobin also induces the release of tPA from endothelium.
Due to its specific action on fibrinogen and its ability to clot platelet-rich plasma without affecting the integrity and functions of the platelets, and thanks to its insensitivity to thrombin inhibitors, batroxobin has found several applications as a tool in blood coagulation research and diagnosis. Batroxobin can be used to determine fibrinogen in plasma, to measure the batroxobin clotting time (Reptilase time) as a heparin-insensitive parallel to the thrombin time, to investigate dysfibrinogenemia, and to test the contractile system of platelets.
EcarinCatalogue Number: 116-01
Size: 50 EU
For the determination of Prothrombin and Hirudin. Specifically activates prothrombin via meizothrombin.
ConvulxinCatalogue Number: 119-02
Size: 50 ug
For activation of human platelets via GPVI-receptor. Useful in studies on platelet receptors.
RVV-Factor V ActivatorCatalogue Number: 121-03
Size: 1,000 U
For activation and determination of Factor V.
RVV Factor X ActivatorCatalogue Number: 121-06
Size: 3 x 5 U
For the determination of Factor X and for screening of Lupus Anticoagulants.