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DSM Pentapharm

Snake Venom Enzymes

Batroxobin

Catalogue Number: 101-04
Size: 100 BU

 

Batroxobin is a thrombin-like proteolytic enzyme isolated from the venom of Bothrops atrox Maranhoa. It splits the 16 Arg-17 Gly bond in the Aα-chain of fibrinogen and causes the release of fibrinopeptide A and the formation of fibrin I monomer or Des-AA-monomer which spontaneously aggregates into a clot of fibrin I. Batroxobin also induces the release of tPA from endothelium.

Due to its specific action on fibrinogen and its ability to clot platelet-rich plasma without affecting the integrity and functions of the platelets, and thanks to its insensitivity to thrombin inhibitors, batroxobin has found several applications as a tool in blood coagulation research and diagnosis. Batroxobin can be used to determine fibrinogen in plasma, to measure the batroxobin clotting time (Reptilase time) as a heparin-insensitive parallel to the thrombin time, to investigate dysfibrinogenemia, and to test the contractile system of platelets.

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Protac

Catalogue Number: 113-01
Size: 5 x 3 U

A fast acting protein C activator.

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Ecarin

Catalogue Number: 116-01
Size: 50 EU

For the determination of Prothrombin and Hirudin. Specifically activates prothrombin via meizothrombin.

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Convulxin

Catalogue Number: 119-02
Size: 50 ug

For activation of human platelets via GPVI-receptor. Useful in studies on platelet receptors.

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RVV-Factor V Activator

Catalogue Number: 121-03
Size: 1,000 U

For activation and determination of Factor V.

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RVV Factor X Activator

Catalogue Number: 121-06
Size: 3 x 5 U

For the determination of Factor X and for screening of Lupus Anticoagulants.

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Protac Solution

Catalogue Number: 113-05
Size: 10 U

A fast acting Protein C activator.

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