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Human Prothrombin (Factor II)

Catalogue Number: HP 1002
Size: 9.0 mg

Prepared from fresh frozen human plasma. Human Prothrombin is a glycoprotein of molecular weight 72,000 and consists of a single polypeptide chain. Activation of Human Prothrombin by Human Factor Va, Human Factor Xa and phospholipids yields the serine protease Human Alpha Thrombin. Human Prothrombin purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol.

 

Human Prothrombin

Buffer Composition = 20 mM Tris-HCl / 0.1 M NaCl / pH 7.4

Extinction Coefficient (1 %) = 13.6

One unit = 90 ug

Molecular Weight = 72,000 daltons 

Supplied LYOPHILIZED. Shipped at ambient temperature.

 

References

1. Suttie JW, Jackson CM: Prothrombin structure, activation, and biosynthesis. Physiol Rev 1977 57(1): 1-70

 

 

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