News

NEW PRODUCT - "AggreCOLL" Horse Collagen Type 1 (2026-04-13)
ERL is pleased to announce the launch of our NEW Horse Collagen Type 1 for research use.

The reagent is ideally suited for platelet aggregation studies.

AggreCOLL
FIB 3 (2026-03-25)
Enzyme Research's Human Fibrinogen vWF Plasminogen & Fibronectin depleted was used in the recent research entitled 'Unraveling the molecular mechanism of in situ surface-initiated thrombogenesis'. JTH Feb 2026
Human FXII (2026-03-25)
Human Factor XII was used in the research in the article 'Thiol isomerase ERp46 catalyzes the disulfide formation of coagulation factor XII enhancing its activity' published in the Journal of Thrombosis & Haemostasis.JTH Feb 2026
Human GP2b3a (2026-01-21)
ERL's Human GP2b3a was used in a recent study 'Significance of the amino acid at position 2561 in the C4 domain of von Willebrand factor' published in the Journal of Thrombosis & Haemostasis. JTH Dec 2025
Human Factor XIa (2025-11-12)
Human Factor XIa from ERL was used in 'A first-in-human study of NXT007, a next-generation, activated factor VIII-mimetic bispecific antibody, in healthy participants' study. JTH Oct 25
Multiple ERL products used in joint research (2025-11-12)
Human FXI, FXII, FXIIa, thrombin & corn trypsin inhibitor were used in a recent study in Ontario Canada. 'Effects of milvexian alone or with heparin on catheter-induced clotting and thrombin generation'. JTH Oct 25
Multiple ERL products used in joint research (2025-10-15)
The article 'Apolipoprotein A-IV regulates coagulation and ischemic stroke by potentiating activated protein C' details the use of Enzyme Research Laboratories products; Human Alpha Thrombin, Human Plasmin, Factor XIIa, kallikrein, Factor IXa, Factor VIIa, Factor Xa, Factor XIa, Activated Protein C and Anti Human Protein C. JTH Sept 2025
Human FXa (2025-10-08)
ERL's Human Factor Xa was used in the research carried out by the Saint Louis University School of Medicine. Report in the September 2025 issue of JTH. JTH Sept 2025
Human Factor X & Pefachrome FXa (2025-09-10)
Both products were used in the work described in the article "Pathways regulating the levels of tissue factor-positive extracellular vesicles and activation of coagulation in endotoxemic mice" JTH Aug 2025
Peak 2 Purified Fibrinogen (2025-07-30)
Peak '2' Fibrinogen was used as a calibrator as described in a recent article in the Journal of Thrombosis & Haemostasis. ( Association of fibrinogen α_E, fibrinogen γ', and sialylated fibrinogen with development of ischemic stroke in patients with recently diagnosed type 2 diabetes)
Emicizumab Calibrator (2025-06-18)
R² Diagnostics' Emicizumab Calibrator plasma used as a specific calibrator in the recent article in Journal of Thrombosis & Haemostasis. JTH May 2025
Human Fibrinogen & Glu-plasminogen (2025-05-07)
Human fibrinogen (plasminogen-depleted, von Willebrand factor (VWF)–depleted, and fibronectin-depleted) and Glu-plasminogen were obtained from Enzyme Research Laboratories for the recent article in the Journal of Thrombosis & Haemostasis.JTH April 2025
Human FXa (2025-03-05)
An article in the latest Journal of Thrombosis & Haemostasis 'Citrullination of tissue factor pathway inhibitor alpha by peptidylarginine deiminase 4 impairs its natural anticoagulant activity toward factors Xa and VIIa/tissue factor and reduces binding to its cofactor protein S' describes using ERL's Human Factor Xa in their research.

JTH Feb 2025
Factor X & Factor VIIa (2024-12-11)
A recent article in the Journal of Thrombosis & Haemostasis 'Small molecules targeting GRP78 mitigate anti-GRP78 autoantibody - mediated tissue factor procoagulation activity in cultured endothelial cells' describes using ERL's FX & FVIIa in their research. JTH November 2024
Russel's Viper Venom (2024-10-23)
Enzyme Research's Russel's Viper Venom was used in recent research as described in the report 'Conformation of factor Xa in solution revealed by single-molecule spectroscopy.' JTH Journal Oct 24
Multiple products used in new Factor XII study (2024-09-25)
An article entitled 'Factor XII contact activation can be prevented by targeting 2 unique patches in its epidermal growth factor-like 1 domain with a nanobody' includes use of Human Factor XII, human prekallikrein, human plasma kallikrein, human factor XI, human factor X and Alpha FXIIa from Enzyme Research Laboratories. Supplementary Materials, JTH Sept 2024
Emicizumab Evaluation (2024-08-07)
An article has been published in JTH 'Multicenter evaluation of the hemostatic activity of emicizumab in patients with severe hemophilia A'. The Emicizumab calibrator was obtained from R2 Diagnostics. JTH July 2024
Human Plasma Activated Protein C (2024-08-07)
Purified Human Plasma Activated Protein C (APC) obtained from Enzyme Research was used in the experiments described in 'An orthosteric/allosteric bivalent peptide agonist comprising covalently linked protease-activated receptor-derived peptides mimics in vitro and in vivo activities of activated protein C'. JTH July 2024
RGR-XaChrom substrate (2024-07-31)
RGR-XaChrom substrate supplied by Enzyme Research Laboratories was used in research to determoine whether Emicizumab promotes factor Xa genetration on endothelial cells. Journal of Thrombosis & Haemostasis
Human alpha-thrombin, Gamma Thrombin & Plasmin (2024-07-31)
ERL's Human Alpha Thrombin, Gamma Thrombin and Plasmin were used in recent research 'A specific fluorescence resonance energy quenching-based biosensor for measuring thrombin activity in whole blood'. June 24 Journal of Thrombosis & Haemostasis
Thrombin activation of the factor XI dimer..... (2024-05-22)
Enzyme's Human Prekallikrein was used in the fluorescence resonance energy transfer assay.JTH May 2024 Volume 22 Number 5
Targeting of coagulation factors XII & XI ........ (2024-05-22)
Enzyme Research Laboratories Prekallikrein and Single Chain High MW Kininogen were used in the real-time FXIIa generation in a purified system and in pooled human plasma.Journal of Thrombosis & Haemostasis
Bovine Factor V/Va, Xa & Human Prothrombin, FX, FVIIa (2024-05-22)
Human and Bovine proteins from Enzyme Research were used in research in a joint collaboration entitled 'Extracellular vesicles from activated platelets possess a phospholipid-rich biomolecular profile and enhance prothrombinase activity'. Journal of Thrombosis & Haemostasis May.
Interplay of fibrinogen alphaEC globular domains... (2024-04-03)
ERLs Human α-thrombin and Human FXIII were used in a study to reveal how the molecular structure impacts the structure & mechanics of fibrin networks.Journal of Thrombosis & Haemostasis.
Hemostatic activity in hemophilia A monkeys (2024-03-06)
ERLs HFIXa & HFX used in Enzymatic assay for FIXa-catalysed FX activation. Supplementary Materials - JTH
High Molecular weight kininogen interactions (2024-02-14)
ERL's Factor XII, Factor XI, Prekallikrein and Single Chain High MW Kininogen feature in a recent publication.Journal of Thrombosis & Haemostasis
Tumor cell-induced coagulation activation (2024-02-14)
ERL's Corn Trypsin Inhibitor appears in a recent publication. Supplementary Materials - JTH
Plasma-purified Beta2 glycoprotein 1 (2024-01-10)
ERL's Human Beta2 glycoprotein 1 appears in recent publication. Science Direct
Protein S, Factor Xa, thrombin (2024-01-10)
ERL's Protein S, Factor Xa and thrombin feature in a recent publication. JTH Journal
Purified Fibrinogen & Plasminogen (2024-01-10)
ERL's Purified Fibrinogen and Plasminogen appears in a recent publication. JTH Journal
Pefakit APC-R Factor V Leiden (2020-01-29)
ERL is pleased to annouce DSM Pentapharms' Pefakit APC-R Factor V Leiden. The highly specific kit is a plasma based functional assay for the determination of resistance of Factor Va to inactivation by Activated Protein C (APC) caused by the Factor V Leiden mutation.

For further details please click on the ink below.

https://www.enzymeresearch.co.uk/product/pefakit-apc-r-factor-v-leiden-3-x-40-tests/403/
NEW PRODUCT - Recombinant Human Alpha Thrombin (2019-02-11)
ERL is pleased to annouce the launch of a NEW recombinant Human Alpha Thrombin for research use.

Please check out the listing below for further details.

https://www.enzymeresearch.co.uk/product/human-alpha-thrombin-recombinant/451/
Sole Distributor UK / Ireland (2018-12-14)
ERL has recently been appointed as sole distributor in the UK / Ireland for DSM Pentapharm.

DSM Pentapharm has a long-standing tradition as an innovative and reliable supplier of active ingredients for the pharmaceutical and diagnostic industry.
Stablex (2018-12-14)
Stablex - An inert stabiliser for enzymes and proteins.
Human Alpha Thrombin (2016-03-14)
ERL's purified plasma derived human alpha thrombin features in a recent publication.
http://onlinelibrary.wiley.com/d…/10.1111/jth.13222/abstract
Human Factor XIa (2016-01-08)
ERL's HFXIa features in recent publication http://onlinelibrary.wiley.com/doi/10.1111/jth.13134/abstract
FREE Coagulation Cascade Mouse Mat (2015-03-19)
To receive your free Coagulation Cascade Mouse Mat email info@enzymeresearch.co.uk
Human Factor XIa (2014-03-05)
ERL's HFXIa features in recent publication. http://onlinelibrary.wiley.com/doi/10.1111/jth.12452/full
RAT TAIL COLLAGEN (2014-02-04)
Enzyme Research Laboratories UK is proud to announce the launch of it's new cell culture product, RAT TAIL COLLAGEN - Type I (STERILE). For information and pricing please contact; info@enzymeresearch.co.uk
Twitter (2013-04-18)
Please follow us on Twitter www.twitter.com/enzymeuk
Facebook (2013-04-18)
Please visit our new Facebook page www.facebook.com/EnzymeResearchLaboratories to catch up on all our latest news.